Tag: QT prolongation

Antimalarial Medications: QT and CYP Interactions You Can't Ignore

Antimalarial Medications: QT and CYP Interactions You Can't Ignore

Antimalarial drugs like hydroxychloroquine and artemether-lumefantrine can cause dangerous heart rhythms when combined with other medications. Learn which drugs interact, who’s at risk, and how to stay safe.

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Dofetilide and Cimetidine: Why This Drug Pair Can Trigger Deadly Heart Rhythms

Dofetilide and Cimetidine: Why This Drug Pair Can Trigger Deadly Heart Rhythms

Dofetilide and cimetidine together can cause deadly heart rhythms. This well-documented interaction raises dofetilide levels by up to 100%, triggering QT prolongation and torsades de pointes. Safe alternatives exist - and this combo is absolutely contraindicated.

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